Team

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Mario Ledda received his Master Degree in Biological Science in 2002. He obtained a Ph.D in Neuroscience in 2007. Cellular and molecular biology researcher at the Institute of Translational Pharmacology (IFT-CNR) since 2008. In 2010 he obtained a Research fellowship, “short-term mobility 2010” for a collaborative research project to explore cell-mediated delivery of anti-cancer therapeutics using modified erythrocytes at the “Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, USA”.  He is coordinator of the CNR "TECH4BIO" Inter-Institute Virtual Laboratory. His scientific interest is focused on multipotent stem cells characterization and their interaction with biomaterials by the analysis of biocompatibility, cell friendly and cell differentiation response for the development of innovative protocols for the use of stem cells in Translational Medicine and Tissue Engineering. Over the last five years his interest has been also directed to the development of new diagnostic and therapeutic systems for applications in oncology and regenerative medicine based on the use of bio-nanotechnology. Tutor of graduating students and author of about 40 peer-reviewed scientific papers published on international journals and contributor to scientific books. Invited speaker and organizing committee member of international conferences. Academic Editor for Evidence-Based Complementary and Alternative Medicine journal and European remote evaluator. Reviewer of published scientific papers related to the Regenerative Medicine Field on international journals.

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Giovanni Longo received his Master Degree in Physics in 2000. He obtained a Ph.D in Matter Structure in 2006. In 2010 he has joined the LPMV at the EPFL in Switzerland as Research Assistant. Since 2015 he is full researcher at the Istituto di Struttura della Materia of the Italian National Research Council (ISM-CNR). His research has focused on the characterization of nanostructures and of nanosized systems (mainly of biological and medical interest). He is an expert in scanning probe microscopies and high-resolution characterization techniques, with a particular focus in the interdisciplinary study of biology, microbiology and medicine samples. For instance, he has employed several techniques (XPS, AFM and quantitative fluorescence) to develop and characterize a DNA biosensor on a crystalline silicon substrate. More recently, he has addressed the development of nanobiosensors and the use of nanotechnologies for innovative investigation of the biological world. He is author of more than 60 papers on international journals several of which on top-level publications. He has contributed in international patents focused on characterization technologies and has been invited to conferences and to present his results in topical lectures at top-tier universities in Europe. He is reviewer of scientific papers related to the fields of biophysics and nanosensor technologies, as well as European remote evaluator.

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Marco GIRASOLE got his master degree in Physics in 1996 at the University “La Sapienza” of Rome (thesis on “Atomic-electronic structures relationship in haemoproteins studied by XANES spectroscopy) and he hold a permanent position at the Italian CNR from 2001 (Institute for the Structure of Matter - ISM). The research activity of dr. Girasole has been exerted in the fields of biophysics and of the nano-sciences, although with a marked interdisciplinary character. Major efforts have been dedicated to the study of structural and functional properties of different cellular or macromolecular biosystems by employing advanced microscopy (including SEM, fluorescence and Scanning Probe Microscopies), spectroscopy (from UV/Vis/NIR to Synchrothron based X-rays) and spectro-microscopy (X-ray and Raman) techniques. Concerning the SPM studies, in particular, the alteration induced by many different stresses (drugs, heavy metals, electromagnetic fields, nano-structured pollutant etc.) or pathologies have been the subject of several investigations. He also applies in the development of microscopy-based methods to determine functional characteristics of biosystems through a nanoscale analysis. This latter approach has been applied to the study of topics such as the development of blood pathologies, the characterization of the aging process in human erythrocytes and the evaluation of the adverse effect of hazardous pollutant on the structure of simple tissues. A parallel activity has been focused on the development of novel SPM instrumentation and in the application of innovative micro and nanosensors for application in cellular and molecular biology.

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Valentina Mussi graduated in Physics in 1998 at the University of Rome Sapienza on Quantum Optics, and obtained a PhD in physics in 2003 at the University of Roma Tre. As a post-doc, she directed the research aimed at the development of biosensors and nanostructured devices for biomedical applications at the NANOMED laboratories of the Physics Department of the University of Genova, where she obtained, in 2011, a position of assistant researcher, also carrying out teaching activities. Since 2012, she is a researcher at the CNR in Rome, first at the Institute of Complex Systems, presently at the Institute of Microelectronics and Microsystems, where she works on the use of vibrational micro-spectroscopy to characterize materials and devices and for bioanalytical and diagnostic applications.

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Andrea Notargiacomo (PhD in Physics in 2003 – ROMA TRE University) is researcher at the Institute of Photonics and Nanotechnologies (IFN) of the CNR in Rome since 2009. He has been in charge of the micro/nano-fabrication facility of IFN-CNR from 2012 to 2014. From 2018 he is responsible for the IFN-CNR activities within the "NanoMicroFab" Open Research Infrastructure which provides technological support to academic and private entities operating in the field of micro/nano-electronics (www.nanomicrofab.eu, Research Infrastructures co-funded by Regione Lazio). He is member of the CNR "TECH4BIO" Inter-Institute Virtual Laboratory since its institution. His research interests include the development of novel solid-state materials and devices at the micro and nanoscale and their exploitation for biological applications. His has expertise in: nanoscale characterization of materials/devices using scanning microscopy (SEM, AFM, C-AFM) and spectroscopy (EDX); nano-fabrication using nano-lithography techniques (EBL, FIB, SPM lithography); synthesis/growth of nanostructures and semiconductor films (ZnO, Ge, Si, SiGe, graphene). He is reviewer for several international scientific journals, and is member of the Editorial board of Applied Sciences Journal (Nanotechnology and Applied Nanosciences Section). He is author of more than 100 scientific publications in peer-reviewed international scientific journals.

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Antonella Lisi, Ph.D in Clinical Pathology in 1999. Permanent position as senior research scientist at the National Research Council (CNR- Rome), since 2001 to present. Head of the “Laboratory of new interdisciplinary therapeutic strategies and innovative technologies for advanced therapies in regenerative medicine”. Author of more than 80 peer-reviewed scientific papers published on international journals, several book chapters and patents. Group leader since 2003 in several national research grant projects.

 

Marialillia Pea is a permanent staff researcher (since 2019) at the Institute for Photonics and Nanotechnologies of the CNR (IFN-CNR) in Rome - (Italy).

In January 2011 she obtained the PhD Degree in Physics from Roma TRE University working on material growth, fabrication and morphological and electrical characterization of low dimensional devices based on VI group semiconductors. Subsequently, she held a research fellowship at the NEST Laboratory of the “Scuola Normale Superiore” and Nanoscience Institute of the CNR in Pisa working on III-V semiconductor nanowires growth and characterization. In August 2012, she started her scientific activity at IFN-CNR in Rome as a research fellow. She worked on the development of “high-efficiency energy harvesting nanogenerators based on ZnO nanowires” and on “Plasmon-enhanced vibrational circular dichroism”.

She has consolidated expertise in diverse research areas of solid-state physics and devices: material growth (dielectric film deposition, semiconducting nanostructures and omo/heterostructures), micro- and nano-fabrication techniques, morphological and electrical characterization of materials and device. She is also involved in research activities on device fabrication, metamaterials and functionalised surfaces for biosensing.

She is co-founder of the CNR "TECH4BIO" Inter-Institute Virtual Laboratory since its institution in 2013.

 

Adele De Ninno Since 2020 she is a researcher at the CNR-Institute for Photonics and Nanotechnologies.
Her primary research interests include microfluidics-based approaches for mimicking complex biological processes, organs-on-chips, especially for onco-immunology applications and lab-on-chip devices for point-of-care diagnostic applications and single-cell analysis. She is actually the unit coordinator of a regional project involving the realization of microfluidic devices for single cell analysis and sorting.

She is Review Editor for Biofabrication-Frontiers in Bioengineering and Biotechnology. She is cofounder of CNR Tech4Bio interinstitute group, member of EurOoC (European Organ-on-Chip Society), co founder and coordinator of  ‘’Technology Thematic Table’’ of the Italian Organ-on-Chip Society (SIOoC).

 

Francesca Romana Bertani obtained Master Degree in Physics and then PhD in Human Pathology at Sapienza University of Rome and Advanced Course on Flow Cytometry from Milan University-Maggiore Hospital. She’s currently a researcher at the Institute for Photonics and Nanotechnologies of CNR. Her main scientific interest and expertise reside at the interface of applied physics and biomedicine, in particular for the development of technologies (optical microscopy, spectroscopy, multispectral imaging, organ on a chip) and approaches (label free, multivariate data analysis) to investigate complex biological processes (immunity, differentiation, pathology). She is founding partner and has been coordinator of the CNR inter-department group Tech4Bio (www.tech4biolab.eu) which organizes every two years Biophysics@Rome conference (http://www.biophysicsatrome.org/). She is founding partner of SiOOC (Società Italiana Organs On Chip).

Recently her activity in European (www.phasmafood.eu) and national projects has included the development of techniques to characterize food matrices using combined optical approaches and data analysis to investigate contamination, authenticity, fraud.

She is involved in collaborations and outreach activities and projects with schools, interest group, general public (Maker Faire Rome, Festival della Scienza Genova).

 

Annalisa Convertino, researcher at the Institute of Microelectronics and Microsystems. Skills: Fabrication of nanostructured interface for biological systems and related devices, in particular as recording electrodes for live cells and surface enhanced Raman substrates. 

 

Luca Maiolo, researcher at the Institute of Microelectronics and Microsystems. Skills: Micro and nanofabrication of biodevices and biosensors on flexible and ultra-flexible substrates; brain implant

fabrication and signal acquisition; biosensor characterization.

 

Luca Businaro, I'm a Micro and nanotechnology scientist with more than ten years’ experience in development of top-down fabrication techniques and their exploitation in several research and industrial fields with particular regard to photonics, microfluidics and bio-medical applications. From Oct 2007 ti Dec 2010, I tought micro and nano fabrication techniques, as contract professor, at the University of Trieste (Faculty of Medicine).

Currently my research interests concerns the applications of micro and nanofabrication (mainly electron beam and imprinting lithography) to cellomics and living cells spectroscopy.

My primary duties involve the development and exploitation of x-ray, electron beam and focussed ion beam lithographies and related clean room processes aimed to chemical and biological applications. During the past decade I acquired a particular expertise in all these fabrication techniques. Thanks to the interdisciplinary nature of the synchrotron working environment I got involved in projects which span several research fields ( photonics, diffractive optical elements and, more recently, mainly microfluidic and bio-nano devices). Now I coordiante the Eureka project “Miniaturized Bragg Mirror on Silicon Chip”, a bilateral Italy-Israel project and I'm partner in an Italian Cancer Research Association (AIRC) project.

 

Annamaria Gerardino. Degree in Physics and PhD degree in Electronic Engineering . She is a researcher at CNR since 1997 and she is in the team responsible of the electron beam lithography system installed at CNR-IFN. Her activity is mainly on the development of nanofabrication processes for photonic, biophotonic and spintronic devices among which photonic crystal based device and more recently microfluidic devices for cell on chip studies. She is  Scientific Responsible in H2020 project PhasmaFOOD and part of the COST action MP1401. She has been responsible for CNR in  FP6 Network of Excellence ePIXnet (European Network of Excellence on Photonic Integrated Component and Circuits) and FP6 Marie Curie Action, ProMiNaS Prototyping in the Micro and Nano Scale) and she is now involved in other international and national projects. She is also in the Scientific committee of :Micro and Nano Engineering (MNE) International Conference since 2008; Biophysics@Rome Conference  since 2014; Nanophotonics and Micro/Nano Optics International Conference since 2016.

 

Massimiliano Benetti  (CNR - IMM )

Domenico Cannatà  (CNR - IMM )

Simone Dinarelli (CNR - ISM )

Fabio Di Pietrantonio CNR - IMM )